Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984025 | 0.87 | KDM5B (0.44) | ALDH1A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL11530672 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL24218501 | 0.79 | LMNA (0.42) | ALDH1A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL31141612 | 0.78 | RAB9A (0.42) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL24925660 | 0.76 | CKS1B (0.48) | ALDH1A1CYP3A4CA12CA1CA2 | |
| SCHEMBL25234167 | 0.74 | CYP1A2 (0.49) | ALDH1A1LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL5364037 | 0.74 | LMNA (0.56) | ALDH1A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL2642000 | 0.73 | CYP2C9 (0.53) | ALDH1A1LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL6880667 | 0.72 | CA12 (0.55) | ALDH1A1LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL6881495 | 0.72 | P2RY12 (0.49) | ALDH1A1LMNACYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022696-A1 | SMALL MOLECULE INHIBITORS OF AUTOPHAGY AND HISTONE DEACTYLASES AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230022696-A1 | SMALL MOLECULE INHIBITORS OF AUTOPHAGY AND HISTONE DEACTYLASES AND USES THEREOF | HDAC5, HDAC4, HDAC7 | ALDH1A1 2087/4885HSD17B10 304/4885LMNA 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.