Sugi Predict

Sugi Predict / Compounds / SCHEMBL2492587

SCHEMBL2492587

SCHEMBL2492587

N#CNC(Cc1ccccc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 5/20 0.57
▸ NPSR1 Q6W5P4 1/20 0.51
▸ CTSS P25774 3/20 0.51
▸ ACE P12821 2/20 0.51
▸ CPA1 P15085 2/20 0.51
▸ ACE2 Q9BYF1 2/20 0.51
▸ CTSK P43235 2/20 0.51
▸ TACR1 P25103 1/20 0.50
▸ NAALAD2 Q9Y3Q0 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CTSL P07711 3/20 0.49
▸ MMP2 P08253 2/20 0.49
▸ CTSB P07858 1/20 0.49
▸ MMP9 P14780 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2492588 1.00 MME (0.57) MMENPSR1CTSSACECPA1
SCHEMBL23249767 1.00 MME (0.57) MMENPSR1CTSSACECPA1
Hydrochloric Acid SCHEMBL7300980 0.98 MME (0.55) MMENPSR1CTSSACECPA1
Hydrochloric Acid SCHEMBL8838224 0.98 MME (0.55) MMENPSR1CTSSACECPA1
SCHEMBL9514743 0.88 CTSS (0.50) MMECTSSCTSKTACR1CTSL
SCHEMBL9514749 0.88 CTSS (0.50) MMECTSSCTSKTACR1CTSL
Valine SCHEMBL7567054 0.87 SLC1A3 (0.48) MMECTSSCTSK
SCHEMBL27849955 0.86 MME (0.43) MMENPSR1CTSSACECPA1
SCHEMBL1792999 0.84 MME (0.54) MMENPSR1ACECPA1ACE2
SCHEMBL1833191 0.84 MME (0.54) MMENPSR1ACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240324466-A1 HIGH VOLTAGE FLEXIBLE MOLECULAR PIEZOELECTRIC DEVICES UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2024-09-26 — — US claimed
WO-2022173969-A1 HIGH VOLTAGE FLEXIBLE MOLECULAR PIEZOELECTRIC DEVICES UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2022-08-18 — — WO claimed
EP-3625243-A1 TAILORED CYCLODEPSIPEPTIDES AS POTENT NON-COVALENT SERINE PROTEASE INHIBITORS Universität Duisburg-Essen (DE) 2020-03-25 — — EP claimed
WO-2018206816-A1 TAILORED CYCLODEPSIPEPTIDES AS POTENT NON-COVALENT SERINE PROTEASE INHIBITORS Universität Duisburg-Essen (DE) 2018-11-15 — — WO claimed
CN-107602495-B A method of preparing chiral amino acid tetrazole compound 盐城工学院 2018-07-24 — — CN claimed
WO-2005122379-A9 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY UNIV CALIFORNIA (US) 2006-03-09 — — WO claimed
WO-2006017619-A2 RECEPTOR-BINDING CYCLIC PEPTIDES AND METHODS OF USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-02-16 — — WO claimed
US-20060029544-A1 Receptor-binding cyclic peptides and methods of use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER (US) 2006-02-09 — — US claimed
EP-1525195-A2 METHOD FOR THE PRODUCTION OF PHENYLALANINE DERIVATIVES Wilex AG (DE) 2005-04-27 — — EP claimed
WO-2004011449-A2 METHOD FOR THE PRODUCTION OF PHENYLALANINE DERIVATIVES WILEX AG (DE) 2004-02-05 — — WO claimed
EP-0635008-B1 PIPERAZIDES OF SUBSTITUTED PHENYLALANINE DERIVATES AS THROMBIN INHIBITORS PENTAPHARM AG (CH) 2002-09-04 — — EP claimed
EP-0868526-A1 NOVEL PROCESS FOR PREPARING N-ACETYL(L)-4-CYANOPHENYLALANINE Ac-(L)-Phe(4-CN)-OH AND N-ACETYL-(L)-p-AMIDINOPHENYLALANINE-CYCLOHEXYLGLYCINE-$g(b)-(3-N-METHYLPYRIDINIUM)-ALANINE Ac-(L)-pAph-Chg-PalMe(3)-NH 2? HOECHST MARION ROUSSEL, INC. (US) 1998-10-07 — — EP claimed
WO-1997022712-A1 NOVEL PROCESS FOR PREPARING N-ACETYL(L)-4-CYANOPHENYLALANINE Ac-(L)-Phe(4-CN)-OH AND N-ACETYL-(L)-p-AMIDINOPHENYLALANINE-CYCLOHEXYLGLYCINE-β-(3-N-METHYLPYRIDINIUM)-ALANINE Ac-(L)-pAph-Chg-PalMe(3)-NH¿2? HOECHST MARION ROUSSEL, INC. (US) 1997-06-26 — — WO claimed
US-5607937-A Piperazides of substituted phenylalanine derivatives as thrombin inhibitors PENTAPHARM AG (CH) 1997-03-04 — — US claimed
EP-0635008-A1 PIPERAZIDES OF SUBSTITUTED PHENYLALANINE DERIVATES AS THROMBIN INHIBITORS Pentapharm A.G. (CH) 1995-01-25 — — EP claimed
WO-1994018185-A1 PIPERAZIDES OF SUBSTITUTED PHENYLALANINE DERIVATES AS THROMBIN INHIBITORS PENTAPHARM AG (CH) 1994-08-18 — — WO claimed
JP-5097793-A — — None — — JP disclosed
US-20260035408-A1 WKYMVm peptide analogues having six residues and uses thereof RESEARCH & BUSINESS FOUND SUNGKYUNKWAN UNIV (KR) 2026-02-05 — — US disclosed
US-4912120-A Containing amine and amide substitution SYNTEX (U.S.A.) INC. (US) 1990-03-27 — — US disclosed
EP-0237082-A2 3,5-disubstituted 4,5-dihydroisoxazoles as transglutaminase inhibitors SYNTEX (U.S.A.) INC. (US) 1987-09-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060029544-A1 Receptor-binding cyclic peptides and methods of use ITGB3, ITGB5, ITGA5 MME 3723/4885NPSR1 372/4885CTSS 4118/4885
US-20260035408-A1 WKYMVm peptide analogues having six residues and uses thereof HNMT, LTK, FPR3 MME 33/4885NPSR1 178/4885CTSS 1991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.