Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 5/20 | 0.41 |
| ▸ | FABP4 | P15090 | 3/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198427 | 1.00 | ACLY (0.41) | ACLYFABP4FABP5PIK3CABRD4 | |
| SCHEMBL31198500 | 0.91 | ACLY (0.38) | ACLYFABP4BRD4ERAP1RAD52 | |
| SCHEMBL24928651 | 0.91 | ACLY (0.38) | ACLYFABP4BRD4ERAP1RAD52 | |
| SCHEMBL24928843 | 0.89 | ACLY (0.38) | ACLYFABP4BRD4ERAP1RAD52 | |
| SCHEMBL30153324 | 0.89 | ACLY (0.38) | ACLYFABP4BRD4ERAP1RAD52 | |
| SCHEMBL24928647 | 0.87 | BRD4 (0.44) | ACLYPIK3CABRD4ERAP1RAD52 | |
| SCHEMBL30153337 | 0.87 | BRD4 (0.44) | ACLYPIK3CABRD4ERAP1RAD52 | |
| SCHEMBL30153306 | 0.83 | ACLY (0.36) | ACLYFABP4RAD52PTK2BSMN1; SMN2 | |
| SCHEMBL24928850 | 0.83 | ACLY (0.36) | ACLYFABP4RAD52PTK2BSMN1; SMN2 | |
| SCHEMBL30845553 | 0.83 | ACLY (0.40) | ACLYSCN9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007188-A1 | PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS | Grey Wolf Therapeutics Limited (GB) | 2023-02-02 | — | — | WO | disclosed |