SCHEMBL712983

SCHEMBL712983

O=CON1C(=O)C=CC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 6/20 0.36
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
FAAH O00519 3/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
GMNN O75496 1/20 0.32
THPO P40225 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
TLR9 Q9NR96 2/20 0.31
HSP90AA1 P07900 1/20 0.31
TP53 P04637 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
XBP1 P17861 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7139394 0.71 MGLL (0.42) MGLLGSK3AGSK3BFAAHALDH1A1
SCHEMBL2493031 0.67
SCHEMBL819470 0.67
SCHEMBL92806 0.65 PARL (0.35)
SCHEMBL19881149 0.63 MGLL (0.35) MGLLGSK3AGSK3BFAAHALDH1A1
SCHEMBL21840474 0.63 MGLL (0.35) MGLLGSK3AGSK3BFAAHALDH1A1
SCHEMBL9728517 0.63 MGLL (0.41) MGLLGSK3AGSK3BFAAHALDH1A1
SCHEMBL5071662 0.63 ALDH1A1 (0.35) MGLLGSK3AGSK3BFAAHALDH1A1
SCHEMBL317848 0.63 MGLL (0.35) MGLLGSK3AGSK3BFAAHALDH1A1
SCHEMBL28365624 0.63 MGLL (0.35) MGLLGSK3AGSK3BFAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824897-A A kind of polyamidoimide and preparation method thereof 株洲时代新材料科技股份有限公司 2019-05-31 CN claimed
CN-108892631-A A kind of heat stabilizer and its synthetic method for PVC 广州臻莱迈新材料科技有限公司 2018-11-27 CN claimed
EP-1597271-B1 PEPTIDES DIRECTED AGAINST ANTIBODIES, WHICH CAUSE COLD-INTOLERANCE, AND THE USE THEREOF MAX DELBRUECK CENTRUM (DE) 2013-03-06 EP claimed
CN-101698736-B Modification method for enhancing polarity and flowability of polypropylene UNIV SOUTH CHINA TECH 2011-10-05 CN claimed
CN-101698736-A Modification method for enhancing polarity and flowability of polypropylene UNIV SOUTH CHINA TECH 2010-04-28 CN claimed
CN-101611320-A Method for detecting antibodies in body fluids by immunoreaction of glycoprotein 2(GP2) from zymogen granules of pancreas for diagnosing inflammatory bowel disease and chronic pancreatitis GA GENERIC ASSAYS GMBH (DE) 2009-12-23 CN claimed
CN-100360554-C peptide conjugates UNIV KEIO (JP) 2008-01-09 CN claimed
CN-1303130-C Process for producing polymerizable polybranched polyester DAINIPPON INK & CHEMICALS (JP) 2007-03-07 CN claimed
CN-1747967-A Peptide conjugate UNIV KEIO (JP) 2006-03-15 CN claimed
CN-1714113-A Process for producing polymerizable polybranched polyester DAINIPPON INK & CHEMICALS (JP) 2005-12-28 CN claimed
EP-0507348-B1 Superoxide dismutase derivatives KURARAY CO (JP) 1997-07-09 EP claimed
US-5532171-A PHENOTHIAZINE DYES FOR PHOTODYNAMIC THERAPY OF CANCER OR IMMUNOASSAY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-07-02 US claimed
US-5360914-A Intermediates for superoxide dismutase derivatives KURARAY CO., LTD. (JP) 1994-11-01 US claimed
US-5344928-A Phenothiazine compounds for cancer treatment or immunoassay using chemiluminescence TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-09-06 US claimed
US-5238837-A Antiinflammatory agents, antiulcer agents KURARAY CO., LTD. (JP) 1993-08-24 US claimed
EP-0510668-A2 Phenothiazine derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-28 EP claimed
EP-0507348-A2 Superoxide dismutase derivatives KURARAY CO., LTD. (JP) 1992-10-07 EP claimed
JP-4253958-A None JP disclosed
EP-0228810-A1 Enzyme immunoassay method for epidermal growth factor NIHON CHEMICAL RESEARCH KABUSHIKI KAISHA also known as JAPAN CHEMICAL RESEARCH CO., LTD (JP) 1987-07-15 EP disclosed
US-4495151-A Element for immunoassay TOYO JOZO KABUSHIKI KAISHA (JP) 1985-01-22 US disclosed