SCHEMBL14699650

SCHEMBL14699650

NNON1C(=O)C=CC1=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2493031 0.69
SCHEMBL10666060 0.67 MGLL (0.42) MGLLGSK3AGSK3BFAAH
SCHEMBL7139394 0.67 MGLL (0.42) MGLLGSK3AGSK3BFAAH
SCHEMBL15892773 0.63 MGLL (0.35) MGLLGSK3AGSK3BFAAH
SCHEMBL461562 0.63
SCHEMBL819470 0.63
SCHEMBL6022398 0.62 NQO1 (0.34) MGLLGSK3AGSK3B
SCHEMBL712983 0.61 MGLL (0.36) MGLLGSK3AGSK3BFAAH
SCHEMBL269178 0.60 ALDH1A1 (0.41) MGLLGSK3AGSK3BFAAH
SCHEMBL9728517 0.59 MGLL (0.41) MGLLGSK3AGSK3BFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346820-B1 OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF SHIONOGI & CO (JP) 2013-02-13 EP disclosed