Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 3/20 | 0.34 |
| ▸ | ESRRB | O95718 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933238 | 0.84 | TSHR (0.37) | TSHRKDM4ERECQLTDP1CHRNB2 | |
| SCHEMBL29203471 | 0.73 | KDM4E (0.41) | TSHRKDM4ERECQLTDP1CYP3A4 | |
| SCHEMBL29203483 | 0.72 | TSHR (0.44) | TSHRKDM4ERECQLTDP1MAPK1 | |
| SCHEMBL29203407 | 0.71 | TSHR (0.37) | TSHRKDM4ERECQLTDP1CHRNB2 | |
| SCHEMBL29203340 | 0.70 | KDM4E (0.41) | TSHRKDM4ERECQLTDP1CHRNB2 | |
| SCHEMBL30240828 | 0.70 | KDM4E (0.41) | TSHRKDM4ERECQLTDP1CHRNB2 | |
| SCHEMBL29203341 | 0.70 | KDM4E (0.41) | TSHRKDM4ERECQLTDP1CHRNB2 | |
| SCHEMBL30240842 | 0.68 | MAPT (0.38) | TSHRKDM4ETDP1CYP3A4CYP2D6 | |
| SCHEMBL30240804 | 0.68 | MAPT (0.38) | TSHRKDM4ETDP1CYP3A4CYP2D6 | |
| SCHEMBL31473801 | 0.67 | CHRNA3 (0.60) | CHRNB2CHRNA4ESRRGESRRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |