Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 3/20 | 0.39 |
| ▸ | ESRRB | O95718 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240828 | 1.00 | KDM4E (0.41) | KDM4ERECQLTDP1CHRNB2CHRNA4 | |
| SCHEMBL29203341 | 1.00 | KDM4E (0.41) | KDM4ERECQLTDP1CHRNB2CHRNA4 | |
| SCHEMBL29203471 | 0.82 | KDM4E (0.41) | KDM4ERECQLTDP1CHRNB2CHRNA4 | |
| SCHEMBL29203407 | 0.80 | TSHR (0.37) | KDM4ERECQLTDP1CHRNB2CHRNA4 | |
| SCHEMBL29203469 | 0.75 | TSHR (0.43) | KDM4ERECQLTDP1CHRNB2CHRNA4 | |
| SCHEMBL31473801 | 0.74 | CHRNA3 (0.60) | CHRNB2CHRNA4ESRRGESRRB | |
| SCHEMBL29203483 | 0.73 | TSHR (0.44) | KDM4ERECQLTDP1TSHRALDH1A1 | |
| SCHEMBL24933238 | 0.72 | TSHR (0.37) | KDM4ERECQLTDP1CHRNB2CHRNA4 | |
| SCHEMBL30434887 | 0.72 | CHRNB2 (0.70) | CHRNB2CHRNA4ESRRGESRRB | |
| SCHEMBL24933767 | 0.71 | ALDH1A1 (0.39) | KDM4ERECQLTDP1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |