Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA3 | P32297 | 4/20 | 0.60 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.57 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.56 |
| ▸ | ESRRG | P62508 | 2/20 | 0.52 |
| ▸ | ESRRB | O95718 | 1/20 | 0.52 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.51 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30434887 | 0.90 | CHRNB2 (0.70) | CHRNA3CHRNB2CHRNA4CHRNB4ESRRG | |
| SCHEMBL2439661 | 0.77 | CHRNB2 (0.85) | CHRNA3CHRNB2CHRNA4CHRNB4CHRNB1 | |
| SCHEMBL13308148 | 0.77 | CHRNB2 (0.85) | CHRNA3CHRNB2CHRNA4CHRNB4CHRNB1 | |
| SCHEMBL23012677 | 0.77 | ALDH1A1 (0.55) | — | |
| SCHEMBL8437376 | 0.76 | CHRNA3 (0.84) | CHRNA3CHRNB2CHRNA4CHRNB4CHRNB1 | |
| SCHEMBL11448032 | 0.76 | ESRRG (0.61) | CHRNB2CHRNA4ESRRGESRRB | |
| SCHEMBL7410490 | 0.76 | CHRNA3 (0.84) | CHRNA3CHRNB2CHRNA4CHRNB4CHRNB1 | |
| Hydrochloric Acid SCHEMBL7459220 | 0.76 | CHRNB2 (0.82) | CHRNA3CHRNB2CHRNA4CHRNB4CHRNB1 | |
| SCHEMBL14174981 | 0.75 | CHRNB2 (0.69) | CHRNA3CHRNB2CHRNA4CHRNB4CHRNB1 | |
| SCHEMBL14577992 | 0.75 | CHRNB2 (0.61) | CHRNA3CHRNB2CHRNA4CHRNB4CHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119730846-A | Kinase modulators and methods of use thereof | 神经元23公司 | 2025-03-28 | — | — | CN | disclosed |