Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2492728 | 0.85 | PDE10A (0.38) | KDRADORA3ADORA2AADORA1RAB9A | |
| SCHEMBL2493080 | 0.75 | KCNN1 (0.42) | KDRRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL191394 | 0.71 | RAB9A (0.58) | MAPK1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4059327 | 0.69 | ALDH1A1 (0.61) | MAPK1ALDH1A1RAB9APPARGNCOA2 | |
| SCHEMBL4057621 | 0.64 | ALDH1A1 (0.66) | ADORA3ADORA2AADORA1ALDH1A1RAB9A | |
| SCHEMBL2580291 | 0.64 | KIF11 (0.57) | ALDH1A1MEN1KMT2AMAPTCYP1A1 | |
| SCHEMBL28462185 | 0.63 | CDK5 (0.38) | KDRALDH1A1RAB9APPARGNCOA2 | |
| SCHEMBL12305708 | 0.63 | GCK (0.47) | KDRMAPK1ALDH1A1RAB9AMEN1 | |
| SCHEMBL12158250 | 0.63 | MAPT (0.61) | MAPK1ALDH1A1RAB9APPARGNCOA2 | |
| SCHEMBL3119959 | 0.62 | CYP3A4 (0.39) | ALDH1A1RAB9APPARGNCOA2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022222-B2 | Glucokinase activators | ARRAY BIOPHARMA, INC. (US) | 2011-09-20 | — | — | US | disclosed |