Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22868087 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL5901932 | 0.81 | GAA (0.68) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL1929282 | 0.78 | CDK5 (0.51) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL5901921 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL24932982 | 0.76 | HSD17B1 (0.36) | — | |
| SCHEMBL3599399 | 0.76 | MAPT (0.55) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL6375741 | 0.72 | L3MBTL1 (0.53) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL1929467 | 0.72 | TSHR (0.46) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL9671945 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL8832434 | 0.71 | ALDH1A1 (0.73) | ALDH1A1MAPTL3MBTL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |