Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB1 | P11230 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240709 | 0.85 | HSD17B2 (0.35) | — | |
| SCHEMBL24933826 | 0.85 | HSD17B2 (0.35) | — | |
| SCHEMBL24933550 | 0.74 | HSD17B2 (0.37) | — | |
| SCHEMBL24933377 | 0.73 | HSD17B2 (0.36) | — | |
| SCHEMBL24933257 | 0.71 | P2RX3 (0.39) | — | |
| SCHEMBL24933705 | 0.71 | P2RX3 (0.39) | — | |
| SCHEMBL24933258 | 0.69 | FPR2 (0.36) | — | |
| SCHEMBL30240828 | 0.69 | KDM4E (0.41) | CHRNB2 | |
| SCHEMBL29203341 | 0.69 | KDM4E (0.41) | CHRNB2 | |
| SCHEMBL29203340 | 0.69 | KDM4E (0.41) | CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |