Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933424 | 0.83 | HDAC3 (0.37) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24933423 | 0.77 | NPY2R (0.31) | — | |
| SCHEMBL24934065 | 0.73 | HDAC3 (0.34) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22890314 | 0.71 | — | — | |
| SCHEMBL24934103 | 0.69 | NPC1 (0.33) | F2PLGMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24934276 | 0.65 | ABCB11 (0.35) | — | |
| SCHEMBL24934219 | 0.63 | PKM (0.42) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24934262 | 0.62 | DDX3X (0.44) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24934270 | 0.62 | TDP1 (0.32) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24934063 | 0.62 | GRM4 (0.37) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009475-A1 | ROCK2 INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-02-02 | — | — | WO | disclosed |