Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24934223 | 0.84 | ABCB11 (0.40) | ABCB11HDAC6 | |
| SCHEMBL24934183 | 0.78 | ABCB11 (0.40) | ABCB11HDAC6 | |
| SCHEMBL24934261 | 0.78 | DDR2 (0.32) | — | |
| SCHEMBL22890314 | 0.69 | — | — | |
| SCHEMBL30163045 | 0.68 | ROCK2 (0.51) | — | |
| SCHEMBL29218319 | 0.68 | ROCK2 (0.51) | — | |
| SCHEMBL24934146 | 0.66 | MAPT (0.34) | ABCB11HDAC6 | |
| SCHEMBL24934129 | 0.65 | F2 (0.32) | — | |
| SCHEMBL24934282 | 0.64 | ABL1 (0.37) | — | |
| SCHEMBL10417210 | 0.64 | ABCB11 (0.67) | ABCB11HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009475-A1 | ROCK2 INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-02-02 | — | — | WO | disclosed |