SCHEMBL24934758

SCHEMBL24934758

CC(=O)COCCCOc1ccc(C(C)C)cc1F

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.41
MRGPRX4 Q96LA9 1/20 0.39
BCHE P06276 6/20 0.39
ACHE P22303 6/20 0.39
PPARG P37231 1/20 0.37
PPARD Q03181 1/20 0.37
NPC1 O15118 1/20 0.37
GAA P10253 1/20 0.37
RAB9A P51151 1/20 0.37
CES2 O00748 1/20 0.36
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
FAAH O00519 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GRM2 Q14416 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24934759 0.88 FFAR1 (0.40) FFAR1MRGPRX4BCHEACHEPPARG
SCHEMBL25063933 0.85 MRGPRX4 (0.40) FFAR1MRGPRX4BCHEACHENPC1
SCHEMBL24935609 0.83 FFAR1 (0.37) FFAR1MRGPRX4BCHEACHENPC1
SCHEMBL24935379 0.81 FFAR1 (0.40) FFAR1MRGPRX4BCHEACHENPC1
SCHEMBL25063926 0.81 KDM4E (0.42) FFAR1MRGPRX4BCHEACHENPC1
SCHEMBL20325825 0.80 FFAR1 (0.41) FFAR1KDM4E
SCHEMBL24935553 0.79 RAB9A (0.47) FFAR1BCHEACHERAB9AL3MBTL1
SCHEMBL18612208 0.78 FFAR1 (0.40) FFAR1
SCHEMBL24935997 0.78 L3MBTL1 (0.40) FFAR1MRGPRX4BCHEACHEGAA
SCHEMBL11994372 0.77 FAAH (0.43) MRGPRX4NPC1RAB9ATHRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4119546-A1 BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF Suzhou Kintor Pharmaceuticals, Inc. (CN) 2023-01-18 EP disclosed