Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12566176 | 0.83 | NR5A1 (0.56) | L3MBTL1PLA2G4BGAA | |
| SCHEMBL12035980 | 0.83 | RAB9A (0.49) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL17445912 | 0.80 | ALDH1A1 (0.66) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL23267023 | 0.79 | LMNA (0.54) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL17445914 | 0.78 | HRH3 (0.64) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9223916 | 0.78 | HTT (0.63) | ALDH1A1USP2MAPK1L3MBTL1PLA2G4B | |
| SCHEMBL9501340 | 0.77 | HTT (0.66) | ALDH1A1L3MBTL1PLA2G4BGAA | |
| SCHEMBL2944311 | 0.77 | HTT (0.66) | ALDH1A1L3MBTL1PLA2G4BGAA | |
| SCHEMBL24674912 | 0.77 | PLA2G4B (0.54) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL8962570 | 0.77 | HTT (0.66) | ALDH1A1L3MBTL1PLA2G4BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |