SCHEMBL24935697

SCHEMBL24935697

CCOCC(F)C(F)COc1ccc(C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.41
TSHR P16473 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NQO1 P15559 1/20 0.40
NPC1 O15118 1/20 0.38
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
RECQL P46063 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
DRD2 P14416 2/20 0.37
DRD4 P21917 2/20 0.37
DRD3 P35462 2/20 0.37
WDR5 P61964 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24935694 0.79 L3MBTL1 (0.42) USP2TSHRMEN1KMT2ANPC1
SCHEMBL15858992 0.77 USP2 (0.49) USP2TSHRMEN1KMT2ANPC1
SCHEMBL20207652 0.75 USP2 (0.47) USP2TSHRMEN1KMT2ANPC1
SCHEMBL4544518 0.74 NQO1 (0.52) TSHRMEN1KMT2ANQO1LMNA
SCHEMBL1496548 0.72 TSHR (0.62) USP2TSHRMEN1KMT2ANPC1
SCHEMBL16348229 0.72 TSHR (0.62) USP2TSHRMEN1KMT2ANPC1
SCHEMBL5779539 0.72 USP2 (0.45) USP2TSHRMEN1KMT2ANQO1
SCHEMBL92159 0.71 NQO1 (0.78) TSHRMEN1KMT2ANQO1KDM4E
SCHEMBL82225 0.71 DRD2 (0.52) MEN1KMT2ANQO1KDM4ELMNA
SCHEMBL16093344 0.70 USP2 (0.47) USP2TSHRMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4119546-A1 BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF Suzhou Kintor Pharmaceuticals, Inc. (CN) 2023-01-18 EP disclosed