Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20640308 | 0.89 | MAPT (0.44) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL21875693 | 0.84 | LMNA (0.41) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL21875692 | 0.84 | LMNA (0.41) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20640322 | 0.82 | LMNA (0.41) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20640319 | 0.82 | LMNA (0.41) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20640325 | 0.80 | LMNA (0.43) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20640307 | 0.80 | LMNA (0.43) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20640300 | 0.79 | LMNA (0.37) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20640312 | 0.79 | DRD4 (0.48) | MAPTSMN1; SMN2LMNANOS1 | |
| SCHEMBL20640338 | 0.78 | LMNA (0.36) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240245675-A1 | PROTEIN SECRETION INHIBITORS | GATE BIOSCIENCE, INC. | 2024-07-25 | — | — | US | disclosed |
| CN-117999256-A | Protein secretion inhibitor | 分子门生物科技公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023010051-A1 | PROTEIN SECRETION INHIBITORS | GATE BIOSCIENCE, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245675-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | MAPT 2526/4885RAB9A 537/4885NPC1 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.