Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24937744 | 0.84 | AKR1C3 (0.62) | AKR1C3MAPK1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL24937791 | 0.82 | AKR1C3 (0.46) | AKR1C3MAPTRECQLHTR1AMAPK1 | |
| SCHEMBL19049589 | 0.81 | NOTUM (0.50) | AKR1C3MAPTRECQLNOTUMTSHR | |
| SCHEMBL13246490 | 0.76 | MGLL (0.53) | AKR1C3KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL23467863 | 0.75 | MTNR1B (0.54) | MAPTRECQLTSHRALDH1A1NPSR1 | |
| SCHEMBL19002664 | 0.75 | TP53 (0.50) | MAPTRECQLMAPK1TSHRKMT2A | |
| SCHEMBL19002655 | 0.75 | MAPT (0.68) | MAPTRECQLMAPK1TSHRKMT2A | |
| SCHEMBL24937187 | 0.74 | AKR1C3 (0.60) | AKR1C3 | |
| SCHEMBL17260627 | 0.74 | MAPT (0.54) | MAPTRECQLMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL24937761 | 0.71 | AKR1C3 (0.58) | AKR1C3MAPTHTR1AMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024778-A1 | STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND | THE UNIVERSITY OF TOKYO (JP) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024778-A1 | STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND | UTS2R, TAS1R1, ULK3 | AKR1C3 689/4885MAPT 958/4885RECQL 2480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.