SCHEMBL24937863

SCHEMBL24937863

O=C(N1CCN(C2CCCCC2)CC1)n1ccnn1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.48
HRH3 Q9Y5N1 5/20 0.48
KCNH2 Q12809 3/20 0.48
POLB P06746 2/20 0.45
HSD17B10 Q99714 1/20 0.45
ALDH1A1 P00352 5/20 0.43
L3MBTL3 Q96JM7 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PHGDH O43175 1/20 0.41
MGLL Q99685 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24937177 0.78 ALDH1A1 (0.44) ALDH1A1MGLLHPGD
SCHEMBL27739891 0.78 HRH3 (0.64) KDM4EHRH3KCNH2POLBHSD17B10
SCHEMBL24937735 0.76 KDM4E (0.51) KDM4EHRH3KCNH2POLBHSD17B10
SCHEMBL28323959 0.75 CYP1A2 (0.43) KDM4EHRH3ALDH1A1MGLLHPGD
SCHEMBL5220449 0.74 MGLL (0.38) MGLL
SCHEMBL27813833 0.72 HRH3 (0.61) KDM4EHRH3KCNH2POLBHSD17B10
SCHEMBL13453747 0.71 POLB (0.58) KDM4EHRH3KCNH2POLBHSD17B10
SCHEMBL10075487 0.71 POLB (0.58) KDM4EHRH3KCNH2POLBHSD17B10
SCHEMBL13088457 0.71 POLB (0.58) KDM4EHRH3KCNH2POLBHSD17B10
SCHEMBL4240780 0.70 MEN1 (0.47) KDM4EHSD17B10ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024778-A1 STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND THE UNIVERSITY OF TOKYO (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024778-A1 STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND UTS2R, TAS1R1, ULK3 KDM4E 4377/4885HRH3 81/4885KCNH2 4417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.