Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23353997 | 0.81 | HDAC4 (0.39) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL17839864 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MAPTPOLBNPC1 | |
| Hydrochloric Acid SCHEMBL29873525 | 0.73 | HDAC4 (0.32) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL23366858 | 0.68 | TRPV1 (0.30) | — | |
| SCHEMBL23354346 | 0.64 | FBP1 (0.40) | ALDH1A1TSHRMAPTPKMNPC1 | |
| SCHEMBL2719121 | 0.64 | KDM4E (0.50) | SMN1; SMN2ALDH1A1TSHRMAPTPKM | |
| SCHEMBL2717847 | 0.64 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MAPTPKMRAB9A | |
| SCHEMBL27400464 | 0.62 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MAPTPKMMEN1 | |
| SCHEMBL17859551 | 0.61 | HDAC4 (0.44) | ALDH1A1MAPTNPC1HTTGAA | |
| SCHEMBL10161356 | 0.61 | MAPT (0.54) | SMN1; SMN2ALDH1A1TSHRMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027985-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027985-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | ADAMTS7, MMP7, ADAMTS1 | SMN1; SMN2 3772/4885ALDH1A1 2009/4885TSHR 2230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.