SCHEMBL24938723

SCHEMBL24938723

Cc1nc(C2(CNC(O)OC(C)(C)C)NC(=O)NC2=O)c(C)s1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADAMTS7 Q9UKP4 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24927849 0.79 ADAMTS7 (0.53) ADAMTS7
SCHEMBL23354086 0.77 ADAMTS7 (0.56) ADAMTS7
SCHEMBL23371329 0.72 ADAMTS7 (0.44) ADAMTS7
Hydrochloric Acid SCHEMBL23354184 0.71 ADAMTS7 (0.43) ADAMTS7
SCHEMBL23354364 0.67 ADAMTS7 (0.50) ADAMTS7
SCHEMBL24927820 0.66 ADAMTS7 (0.41) ADAMTS7
SCHEMBL23361479 0.65 ADAMTS7 (0.55) ADAMTS7
SCHEMBL23354019 0.62 ADAMTS7 (0.43) ADAMTS7
SCHEMBL24927869 0.60 ADAMTS7 (0.43) ADAMTS7
SCHEMBL24927992 0.59 ADAMTS7 (0.33) ADAMTS7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230027985-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS BAYER AKTIENGESELLSCHAFT (DE) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027985-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS ADAMTS7, MMP7, ADAMTS1 ADAMTS7 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.