Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16869941 | 0.81 | OPRM1 (0.44) | GAAHDAC4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16767685 | 0.76 | OPRM1 (0.43) | BACE1KMT2AOPRM1OPRL1BCHE | |
| SCHEMBL16867365 | 0.73 | OPRL1 (0.44) | OPRM1OPRK1OPRD1OPRL1 | |
| Hydrochloric Acid SCHEMBL28746625 | 0.72 | MEN1 (0.50) | GAATSHRCYP2D6HIF1AKMT2A | |
| SCHEMBL11806132 | 0.71 | HDAC4 (0.41) | TSHRHDAC4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6552316 | 0.71 | HTR2A (0.39) | GAAKMT2ALMNAOPRM1OPRK1 | |
| SCHEMBL16593764 | 0.70 | HDAC4 (0.54) | TSHRCYP2D6HDAC4SLC6A2SLC6A4 | |
| SCHEMBL14376716 | 0.70 | GAA (0.49) | GAATSHRCYP2D6HIF1ASLC6A2 | |
| SCHEMBL7930135 | 0.69 | TSHR (0.78) | TSHRCYP2D6HIF1ASLC6A4CA12 | |
| SCHEMBL19373091 | 0.69 | GAA (0.47) | GAATSHRCYP2D6HIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560422-B2 | Sulfonamide-containing linkage systems for drug conjugates | ZYMEWORKS INC. | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560422-B2 | Sulfonamide-containing linkage systems for drug conjugates | MPST, TPST2, SULT1A1 | GAA 998/4885TSHR 2211/4885CYP2D6 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.