Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | G6PD | P11413 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | CCR6 | P51684 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939849 | 0.86 | TSHR (0.53) | ALDH1A1TDP1NPSR1HTTHSP90AA1 | |
| SCHEMBL17301073 | 0.84 | DDAH1 (0.58) | ALDH1A1TDP1NPSR1HTTHSP90AA1 | |
| SCHEMBL21859084 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TDP1NPSR1HTTHSP90AA1 | |
| SCHEMBL14502327 | 0.79 | TDP1 (0.56) | ALDH1A1TDP1NPSR1HPGDMEN1 | |
| SCHEMBL24939676 | 0.77 | MYC (0.56) | ALDH1A1TDP1NPSR1HTTHSP90AA1 | |
| SCHEMBL24939671 | 0.76 | DDAH1 (0.53) | ALDH1A1TDP1NPSR1HTTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL11453925 | 0.76 | DDAH1 (0.53) | ALDH1A1TDP1NPSR1HTTHSP90AA1 | |
| SCHEMBL24938792 | 0.76 | MYC (0.60) | ALDH1A1TDP1NPSR1HTTHSP90AA1 | |
| SCHEMBL9155405 | 0.76 | MGLL (0.59) | ALDH1A1TDP1NPSR1HTTHSP90AA1 | |
| SCHEMBL21766258 | 0.76 | GAA (0.56) | ALDH1A1TDP1NPSR1HTTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002222-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | 3R VALO, S.E.C. (CA) | 2021-01-07 | — | — | US | disclosed |
| EP-3442943-B1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | 3R VALO S E C (CA) | 2020-10-07 | — | — | EP | disclosed |
| US-10759754-B2 | Aminobenzoic acid derivatives for use as anti-inflammatory agents, anti-metastatic agents and/or anticancer agents | 3R VALO, S.E.C. (CA) | 2020-09-01 | — | — | US | disclosed |
| US-20190127325-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | UNIVERSITÉ DU QUÉBEC À TROIS-RIVIÈRES (CA) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002222-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | NFKBIA, NFKB1, NFRKB | ALDH1A1 324/4885TDP1 3339/4885NPSR1 3458/4885 |
| US-20190127325-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | NFKBIA, NFKB1, NFRKB | ALDH1A1 324/4885TDP1 3339/4885NPSR1 3458/4885 |
| US-10759754-B2 | Aminobenzoic acid derivatives for use as anti-inflammatory agents, anti-metastatic agents and/or anticancer agents | NFKBIA, NFKB1, NFRKB | ALDH1A1 324/4885TDP1 3339/4885NPSR1 3458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.