SCHEMBL24939865

SCHEMBL24939865

O=C(O)C(F)CN1C(=O)C2=C(CCCC2)C1=O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24939871 0.79 LMNA (0.39) LMNAKDM4EMAPT
SCHEMBL24939872 0.76 ALDH1A1 (0.47) LMNAMAPT
SCHEMBL15894720 0.71 PIK3CD (0.44) LMNAKDM4EMAPT
SCHEMBL7503582 0.71 CA12 (0.48) LMNAKDM4EMAPTTSHR
Ethane SCHEMBL11761237 0.69 KDM4E (0.35) LMNAKDM4EMAPTTSHRNPSR1
SCHEMBL19301942 0.68 KDM4E (0.39) LMNAKDM4E
SCHEMBL24939775 0.68 ALDH1A1 (0.57) LMNAKDM4ETSHRNPSR1
SCHEMBL358695 0.68 KDM4E (0.44) LMNAKDM4EHTR7
SCHEMBL5998311 0.67 KDM4E (0.36) LMNAKDM4EMAPT
SCHEMBL5998489 0.66 ALDH1A1 (0.36) LMNAKDM4EMAPTTSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS GFER, LBR, PCNA LMNA 1223/4885KDM4E 1123/4885MAPT 2848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.