SCHEMBL24939872

SCHEMBL24939872

CC1=C(C)C(=O)N(CC(F)C(=O)O)C1=O

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
PKM P14618 1/20 0.47
MAPT P10636 1/20 0.34
APAF1 O14727 3/20 0.33
GRIA1 P42261 1/20 0.32
GRIA2 P42262 1/20 0.32
GRIA4 P48058 1/20 0.32
GRIK5 Q16478 1/20 0.32
PTGS2 P35354 2/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24939867 0.78 ALDH1A1 (0.48) ALDH1A1PKMAPAF1LMNAPOLB
SCHEMBL24939866 0.77 APAF1 (0.31) ALDH1A1PKMMAPTAPAF1LMNA
SCHEMBL24939865 0.76 LMNA (0.39) MAPTLMNA
SCHEMBL15977327 0.69 ALDH1A1 (0.41) ALDH1A1PKMMAPTLMNAPOLB
SCHEMBL7462959 0.67 ALDH1A1 (0.61) ALDH1A1PKMMAPTLMNAPOLB
SCHEMBL14377608 0.67 ALDH1A1 (0.41) ALDH1A1PKMMAPTLMNAPOLB
SCHEMBL21911826 0.65 GAA (0.41) ALDH1A1PKMMAPT
SCHEMBL8892091 0.64 ALDH1A1 (1.00) ALDH1A1PKMPTGS2LMNAPOLB
SCHEMBL5663770 0.64 ALDH1A1 (0.38) ALDH1A1PKMLMNA
SCHEMBL17853989 0.63 ALDH1A1 (0.45) ALDH1A1PKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS GFER, LBR, PCNA ALDH1A1 3757/4885PKM 3080/4885MAPT 2848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.