SCHEMBL358695

SCHEMBL358695

O=C1C2=C(CCCC2)C(=O)N1CO

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
TRIM24 O15164 1/20 0.30
TRIM33 Q9UPN9 1/20 0.30
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11841551 0.84 KDM4E (0.50) KDM4ELMNA
SCHEMBL10262842 0.81 KDM4E (0.42) KDM4ELMNAHTR7
SCHEMBL10031631 0.75 LMNA (0.44) KDM4ELMNATRIM24TRIM33
SCHEMBL9656303 0.75 KDM4E (0.44) KDM4ELMNATRIM24TRIM33HTR7
SCHEMBL7503582 0.75 CA12 (0.48) KDM4ELMNA
SCHEMBL10908051 0.73 HTR7 (0.43) KDM4ELMNAHTR7
SCHEMBL10949823 0.73
SCHEMBL24939775 0.72 ALDH1A1 (0.57) KDM4ELMNA
SCHEMBL21389153 0.71 KDM4E (0.42) KDM4ELMNAHTR7
SCHEMBL22215812 0.70 CASP3 (0.43) KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112939843-B Synthesis method of N-hydroxymethyl-3, 4,5, 6-tetrahydrophthalimide 江苏优嘉植物保护有限公司 2022-04-01 CN claimed
CN-112592777-B Deep groove cleaning solution after 3D NAND structure piece dry etching 湖北兴福电子材料有限公司 2021-09-07 CN claimed
CN-112939843-A Synthesis method of N-hydroxymethyl-3, 4,5, 6-tetrahydrophthalimide 江苏优嘉植物保护有限公司 2021-06-11 CN claimed
CN-112592777-A Deep groove cleaning solution after 3D NAND structure piece dry etching 湖北兴福电子材料有限公司 2021-04-02 CN claimed
CN-111875533-A Preparation method of N-hydroxymethyl-3, 4,5, 6-tetrahydrochysene imine 河南源博新材料有限公司 2020-11-03 CN claimed
EP-1792889-B1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2015-03-04 EP claimed
US-7741511-B2 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US claimed
US-20080009648-A1 PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS SOUDA HIROSHI 2008-01-10 US claimed
EP-1792889-A2 Process for the preparation of carboxylic acid esters Sumitomo Chemical Company, Limited (JP) 2007-06-06 EP claimed
EP-1547995-A1 Process for the preparation of carboxylic acid esters Sumitomo Chemical Company, Limited (JP) 2005-06-29 EP claimed
US-4537897-A PESTICIDES ROUSSEL UCLAF (FR) 1985-08-27 US claimed
EP-0077721-B1 CYCLOPROPANECARBOXYLIC-ACID DERIVATIVES BEARING AN ALKYLTHIOCARBONYL GROUP, THEIR PREPARATION, THEIR USE AS PARASITICIDES FOR PLANTS, ANIMALS, AND LOCI, AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1985-07-03 EP claimed
EP-0048186-B1 CYCLOPROPANE-CARBOXYLIC-ACID DERIVATIVES, THEIR PREPARATION, THEIR USE IN COMBATING VEGETAL PARASITES, ANIMALS AND LOCATIONS, THEIR COMPOSITIONS, AND INTERMEDIATES ROUSSEL-UCLAF (FR) 1985-05-02 EP claimed
EP-0050534-B1 ESTERS OF CYCLOPROPANE-CARBOXYLIC ACIDS RELATED TO PYRETHRIC ACID, THEIR PREPARATION AND USE AS INSECTICIDES ROUSSEL-UCLAF (FR) 1985-04-03 EP claimed
US-4489093-A Insecticidal esters ROUSSEL UCLAF (FR) 1984-12-18 US claimed
US-4478850-A DESTICIDES, NEMATOCIDES, MITICIDES, AND INSECTICIDES ROUSSEL UCLAF (FR) 1984-10-23 US claimed
EP-0041021-B1 CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION, THEIR USE AGAINST PARASITES IN PLANTS AND ANIMALS, THEIR COMPOSITIONS AND THEIR INTERMEDIATES ROUSSEL-UCLAF (FR) 1984-07-25 EP claimed
EP-0038271-B1 CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE IN COMBATING PARASITES OF PLANTS AND ANIMALS, THEIR COMPOSITIONS AND INTERMEDIATES ROUSSEL-UCLAF (FR) 1984-07-04 EP claimed
US-4423243-A Process for the preparation of 2,2-dimethyl-3-vinyl-cyclopropanecarboxylic acids and esters BAYER AKTIENGESELLSCHAFT (DE) 1983-12-27 US claimed
EP-0018894-B1 ESTERS OF ALLETHROLONE DERIVATIVES AND CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1982-02-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009648-A1 PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS ACSL6, ALKBH3, ACSL1 KDM4E 763/4885LMNA 3667/4885TRIM24 3458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.