Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 13/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865923 | 0.86 | CYP2D6 (0.41) | CYP2D6SMN1; SMN2CYP3A4USP2CYP1A2 | |
| SCHEMBL24483922 | 0.83 | CYP2D6 (0.51) | CYP2D6SMN1; SMN2CYP3A4USP2CYP1A2 | |
| SCHEMBL24866029 | 0.82 | VCP (0.41) | VCP | |
| SCHEMBL25089687 | 0.81 | HRH3 (0.39) | VCP | |
| SCHEMBL22520757 | 0.79 | VCP (0.41) | CYP2D6SMN1; SMN2CYP1A2VCPSIGMAR1 | |
| SCHEMBL24475619 | 0.77 | VCP (0.39) | CYP2D6SMN1; SMN2CYP1A2VCPSIGMAR1 | |
| SCHEMBL25101497 | 0.76 | OPRK1 (0.34) | — | |
| SCHEMBL24941988 | 0.75 | CYP2D6 (0.39) | CYP2D6SMN1; SMN2CYP3A4USP2CYP1A2 | |
| SCHEMBL26445329 | 0.75 | CYP2D6 (0.46) | CYP2D6SMN1; SMN2CYP3A4USP2CYP1A2 | |
| SCHEMBL26445336 | 0.75 | CYP2D6 (0.50) | CYP2D6SMN1; SMN2CYP3A4USP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2024-02-29 | — | — | US | disclosed |
| US-20230331722-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-10-19 | — | — | US | disclosed |
| US-11767330-B2 | Citrate salt, pharmaceutical compositions, and methods of making and using the same | FOGHORN THERAPEUTICS INC. (US) | 2023-09-26 | — | — | US | disclosed |
| US-20230142883-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-11 | — | — | US | disclosed |
| US-20230142883-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-11 | — | — | US | disclosed |
| US-11560381-B1 | Compounds and uses thereof | FOGHORN THERAPEUTICS INC. (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331722-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | CYP2D6 3897/4885SMN1; SMN2 368/4885CYP3A4 2977/4885 |
| US-20230142883-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | CYP2D6 3897/4885SMN1; SMN2 368/4885CYP3A4 2977/4885 |
| US-11767330-B2 | Citrate salt, pharmaceutical compositions, and methods of making and using the same | CS, SMARCC2, SMARCC1 | CYP2D6 2726/4885SMN1; SMN2 2332/4885CYP3A4 2243/4885 |
| US-11560381-B1 | Compounds and uses thereof | VHL, TFEB, BECN1 | CYP2D6 3897/4885SMN1; SMN2 368/4885CYP3A4 2977/4885 |
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | CYP2D6 3897/4885SMN1; SMN2 368/4885CYP3A4 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.