Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20225831 | 0.80 | OGA (0.41) | HTR3AHRH4OGAMAPTLMNA | |
| SCHEMBL1505644 | 0.79 | OGA (0.36) | HTR3AHRH4OGAMAPTLMNA | |
| SCHEMBL17404870 | 0.79 | MEN1 (0.40) | HTR3AHRH4OGALMNAMEN1 | |
| SCHEMBL530287 | 0.79 | OGA (0.41) | HTR3AHRH4OGAMAPTLMNA | |
| SCHEMBL17037512 | 0.79 | SIGMAR1 (0.43) | OGAKDM4ESIGMAR1 | |
| SCHEMBL21025738 | 0.79 | HTR3A (0.36) | HTR3AHRH4OGAMAPTLMNA | |
| SCHEMBL1505703 | 0.79 | PANK3 (0.41) | HTR3AHRH4OGAMAPTLMNA | |
| SCHEMBL1505737 | 0.78 | GPR119 (0.50) | KIT | |
| SCHEMBL24827960 | 0.76 | OGA (0.40) | HTR3AHRH4OGALMNANPC1 | |
| SCHEMBL19449799 | 0.76 | OGA (0.45) | HTR3AHRH4OGAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010078-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2023-02-02 | — | — | WO | disclosed |