SCHEMBL2494565

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7919068	0.90	ESR1 (0.66)	CA2CA1ALDH1A1HSD17B10HPGD
	SCHEMBL22050366	0.90	HTR2A (0.50)	CA2CA1ALDH1A1HSD17B10HTR2A
	SCHEMBL2491588	0.85	LPL (0.48)	CA2HTR2APLK1LPLLIPG
	SCHEMBL83869	0.84	CA2 (0.65)	CA2CA1ALDH1A1HSD17B10HTR2A
	SCHEMBL7922249	0.84	PTGS2 (0.75)	ALDH1A1HSD17B10HTR2ASMN1; SMN2ESR1
	SCHEMBL382808	0.84	HTR2A (0.73)	ALDH1A1HSD17B10HTR2AESR1ADRA2A
	SCHEMBL4055722	0.84	CA2 (0.55)	CA2CA1ALDH1A1HSD17B10HTR2A
	SCHEMBL8090819	0.84	UCHL3 (0.56)	CA2CA1ALDH1A1HSD17B10HTR2A
	SCHEMBL9621454	0.84	CA2 (0.50)	CA2CA1ALDH1A1HSD17B10HTR2A
	SCHEMBL13976654	0.84	CA2 (0.43)	CA2CA1ALDH1A1HSD17B10HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.