SCHEMBL24901359

SCHEMBL24901359

O=C(OCc1ccc(Cl)cc1F)C(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 4/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40
TBXA2R P21731 2/20 0.40
PTGS1 P23219 2/20 0.40
CYP2C19 P33261 2/20 0.40
PTGER3 P43115 2/20 0.40
PTGER2 P43116 2/20 0.40
KDM5A P29375 1/20 0.38
KDM5B Q9UGL1 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
HPD P32754 1/20 0.37
GAA P10253 1/20 0.36
VNN1 O95497 1/20 0.36
ERCC1 P07992 1/20 0.36
ERCC4 Q92889 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24945950 0.85 MAOB (0.49) KDM5AKDM5BTDP1
SCHEMBL24901418 0.80 MMP2 (0.43)
SCHEMBL24945949 0.79 MMP2 (0.48) L3MBTL1
SCHEMBL24142279 0.79 ALDH1A1 (0.47) L3MBTL1TDP1GAA
SCHEMBL13034127 0.77 GAA (0.47) PTGER1CYP1A2CYP2C9TBXA2RPTGS1
SCHEMBL24142323 0.77 MAOA (0.43) CYP1A2CYP2C9CYP2C19L3MBTL1GAA
SCHEMBL24901042 0.75 HCAR2 (0.52) MRGPRX4
SCHEMBL24901410 0.75 MMP2 (0.33)
SCHEMBL24901131 0.75 MAOA (0.48) KDM5AKDM5BMRGPRX4
SCHEMBL24901041 0.75 L3MBTL1 (0.47) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed
US-20230019681-A1 POSITIVE RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS HNRNPU, EWSR1, HNRNPR PTGER1 3709/4885CYP1A2 4857/4885CYP2C9 4547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.