Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24946291 | 0.85 | L3MBTL1 (0.44) | ATMCTSSCTSK | |
| SCHEMBL21689917 | 0.78 | PPARG (0.55) | PPARGPPARACYP17A1PTGDR2ADAMTS4 | |
| SCHEMBL2403143 | 0.78 | PPARG (0.55) | PPARGPPARACYP17A1PTGDR2ADAMTS4 | |
| SCHEMBL24945921 | 0.78 | MAPT (0.46) | PPARGPPARACYP17A1DRD2HDAC8 | |
| SCHEMBL2398906 | 0.78 | PPARG (0.55) | PPARGPPARACYP17A1PTGDR2ADAMTS4 | |
| SCHEMBL2309189 | 0.78 | PPARG (0.55) | PPARGPPARACYP17A1PTGDR2ADAMTS4 | |
| SCHEMBL2617177 | 0.78 | PPARG (0.55) | PPARGPPARACYP17A1PTGDR2ADAMTS4 | |
| SCHEMBL24324458 | 0.77 | CYP17A1 (0.57) | PPARGPPARACYP17A1PTGDR2ADAMTS4 | |
| SCHEMBL10890972 | 0.77 | ITGB3 (0.61) | PPARGPPARACYP17A1ITGB3ITGA2B | |
| SCHEMBL2895770 | 0.77 | AKT1 (0.49) | PPARGPPARAATMCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002452-A1 | PROCESS FOR PREPARATION OF TARGETING LIGANDS | Janssen Pharmaceuticals, Inc. (US) | 2023-01-26 | — | — | WO | disclosed |