Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SDCBP | O00560 | 1/20 | 0.44 |
| ▸ | SDC2 | P34741 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24946290 | 0.85 | PPARG (0.50) | ATMCTSSCTSK | |
| SCHEMBL24946398 | 0.84 | L3MBTL1 (0.43) | L3MBTL1SDCBPSDC2ATMHDAC1 | |
| SCHEMBL19930013 | 0.80 | PLAU (0.52) | HDAC1NAMPTCTSSCTSKCTSL | |
| SCHEMBL21533322 | 0.79 | L3MBTL1 (0.49) | L3MBTL1SDCBPSDC2ATMHDAC1 | |
| SCHEMBL10441345 | 0.79 | SDCBP (0.54) | L3MBTL1SDCBPSDC2ATMHDAC1 | |
| SCHEMBL24946310 | 0.78 | MEN1 (0.52) | ATMHDAC1MEN1KMT2ANAMPT | |
| SCHEMBL12463672 | 0.78 | SLC7A5 (0.52) | L3MBTL1SDCBPSDC2ATMHDAC1 | |
| SCHEMBL20038756 | 0.78 | SLC7A5 (0.52) | L3MBTL1SDCBPSDC2ATMHDAC1 | |
| SCHEMBL3180689 | 0.78 | L3MBTL1 (0.61) | L3MBTL1SDCBPSDC2HDAC1NAMPT | |
| SCHEMBL12463287 | 0.78 | SLC7A5 (0.52) | L3MBTL1SDCBPSDC2ATMHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002452-A1 | PROCESS FOR PREPARATION OF TARGETING LIGANDS | Janssen Pharmaceuticals, Inc. (US) | 2023-01-26 | — | — | WO | disclosed |