SCHEMBL2494737

SCHEMBL2494737

OCc1cn(Cc2ccccc2)nn1

nearest known ligand 0.73

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.73
CYP19A1 P11511 10/20 0.66
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
HRH4 Q9H3N8 1/20 0.57
HSP90AB1 P08238 2/20 0.56
KCNMA1 Q12791 1/20 0.55
HDAC1 Q13547 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28329957 0.92 NOTUM (0.63) NOTUMCYP19A1NPC1RAB9AHRH4
SCHEMBL6980467 0.84 NOTUM (1.00) NOTUMCYP19A1HSP90AB1KCNMA1HDAC1
SCHEMBL28863788 0.84 NOTUM (0.71) NOTUMCYP19A1NPC1RAB9AHRH4
SCHEMBL12022159 0.84 KCNMA1 (0.69) CYP19A1NPC1RAB9AHRH4HSP90AB1
SCHEMBL3103838 0.84 CYP19A1 (0.68) NOTUMCYP19A1NPC1RAB9AHRH4
SCHEMBL16831504 0.83 CYP19A1 (0.69) NOTUMCYP19A1NPC1RAB9AHRH4
SCHEMBL16206205 0.83 NOTUM (0.73) NOTUMCYP19A1HSP90AB1HDAC1
SCHEMBL2820182 0.83 NOTUM (0.73) NOTUMCYP19A1NPC1RAB9AHDAC1
SCHEMBL12885309 0.83 NOTUM (0.73) NOTUMCYP19A1NPC1RAB9AHRH4
SCHEMBL16206231 0.83 GBA1 (0.60) NOTUMCYP19A1HRH4KCNMA1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240117095-A1 GRIN LENSES MADE BY 3D PRINTING MONOMER-BASED INKS VADIENT OPTICS, LLC 2024-04-11 US claimed
WO-2024064650-A2 GRIN LENSES MADE BY 3D PRINTING MONOMER-BASED INKS VADIENT OPTICS, LLC (US) 2024-03-28 WO claimed
CN-110483220-B Composite solid propellant and preparation method and treatment method thereof 北京理工大学 2020-08-11 CN claimed
CN-110452358-B Preparation method of triazole-terminated azido polyether 北京理工大学 2020-08-11 CN claimed
US-12592537-B2 Fiber for optical power amplification and/or optical power generation UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2026-03-31 US disclosed
US-12571105-B2 Metallic coated substrates ARMADILLO METAL COATINGS LTD (GB) 2026-03-10 US disclosed
US-20250288970-A1 SOLID SORBENT MATERIALS FUNCTIONALIZED WITH POLYAMINES HAVING OXYGEN-CONTAINING UNITS SELECTED FROM CARBONYL UNITS, HYDROXYL UNITS, AND COMBINATIONS THEREOF GE INFRASTRUCTURE TECHNOLOGY LLC 2025-09-18 US disclosed
EP-4616940-A1 SOLID SORBENT MATERIALS FUNCTIONALIZED WITH POLYAMINES HAVING OXYGEN-CONTAINING UNITS SELECTED FROM CARBONYL UNITS, HYDROXYL UNITS, AND COMBINATIONS THEREOF GE Vernova Technology GmbH (CH) 2025-09-17 EP disclosed
EP-4601786-A1 SORBENT COMPOSITIONS, SYSTEMS, AND METHODS General Electric Technology GmbH (CH) 2025-08-20 EP disclosed
CN-120020618-A Transparent base material with antiglare layer and composition for antiglare layer AGC株式会社 2025-05-20 CN disclosed
WO-2024256789-A1 IN VITRO MODEL OF INFLAMED INTESTINAL BARRIER UNIVERSITE DE FRANCHE COMTE (FR) 2024-12-19 WO disclosed
US-20240335527-A1 VACCINE ADJUVANTS, TRANSFECTION REAGENTS, AND METHODS OF USING THE SAME WISCONSIN ALUMNI RESEARCH FOUNDATION 2024-10-10 US disclosed
US-4137237-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1979-01-30 US disclosed
US-4137234-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1979-01-30 US disclosed
US-4070475-A THIOALKYL-, AMINOALKYL-, AND OXYALKYL- SUBSTITUTED GUANIDINES SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1978-01-24 US disclosed
US-4024271-A INHIBITORS OF HISTAMINE ACTIVITY SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1977-05-17 US disclosed
US-4022797-A PHARMACEUTICALS SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1977-05-10 US disclosed
US-4018931-A INHIBITION OF H-2 HISTAMINE RECEPTORS SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1977-04-19 US disclosed
US-3950333-A HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1976-04-13 US disclosed
US-3950353-A HISTAMINE INHIBITORS SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12571105-B2 Metallic coated substrates SOD1, TET1, TST NOTUM 4498/4885CYP19A1 3359/4885NPC1 4388/4885
US-12592537-B2 Fiber for optical power amplification and/or optical power generation SRMS, VEGFA, HCN4 NOTUM 4555/4885CYP19A1 3398/4885NPC1 3417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.