Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30200508 | 1.00 | MAOA (0.33) | MAOAMAOBMAP2K1HTR2AHTR2C | |
| SCHEMBL29559334 | 0.81 | MAOA (0.33) | MAOAMAOBHTR2AHTR2CHTR2B | |
| SCHEMBL24947657 | 0.81 | MAOA (0.33) | MAOAMAOBHTR2AHTR2CHTR2B | |
| SCHEMBL26758909 | 0.73 | MAOA (0.37) | MAOAMAOBHTR2AHTR2CHTR2B | |
| SCHEMBL6679464 | 0.72 | EED (0.45) | HTR2AHTR2C | |
| SCHEMBL31147744 | 0.72 | P4HB (0.32) | HTR2AHTR2CHTR2BP4HB | |
| SCHEMBL21438585 | 0.72 | — | — | |
| SCHEMBL522658 | 0.71 | APOBEC3G (0.36) | — | |
| SCHEMBL31147754 | 0.70 | MAOB (0.32) | MAOB | |
| SCHEMBL18876064 | 0.69 | TRPA1 (0.38) | MAOAMAOBHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023000834-A1 | BENZIMIDAZOLE OR AZABENZIMIDAZOLE-6-CARBOXYLIC ACID COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2023-01-26 | — | — | WO | disclosed |
| CN-113480534-B | Benzimidazole or azabenzimidazole-6-carboxylic acid compounds and application thereof | 广州必贝特医药股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113480534-A | Benzimidazole or azabenzimidazole-6-carboxylic acid compounds and application thereof | 广州必贝特医药技术有限公司 | 2021-10-08 | — | — | CN | disclosed |