SCHEMBL24947657

SCHEMBL24947657

Fc1c(CBr)ccc2ccoc12

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29559334 1.00 MAOA (0.33) MAOAMAOBHTR2AHTR2CHTR2B
SCHEMBL30200508 0.81 MAOA (0.33) MAOAMAOBHTR2AHTR2CHTR2B
SCHEMBL24947653 0.81 MAOA (0.33) MAOAMAOBHTR2AHTR2CHTR2B
SCHEMBL953406 0.77 MAOA (0.36) MAOAMAOBHTR2AHTR2CHTR2B
SCHEMBL31147744 0.75 P4HB (0.32) HTR2AHTR2CHTR2B
SCHEMBL16048413 0.74 MAOA (0.35) MAOAMAOBHTR2AHTR2CHTR2B
SCHEMBL26758909 0.73 MAOA (0.37) MAOAMAOBHTR2AHTR2CHTR2B
SCHEMBL31630367 0.72 PDE7B (0.33)
SCHEMBL957265 0.72 EED (0.45) HTR2AHTR2C
SCHEMBL31147754 0.70 MAOB (0.32) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023000834-A1 BENZIMIDAZOLE OR AZABENZIMIDAZOLE-6-CARBOXYLIC ACID COMPOUND AND USE THEREOF 广州必贝特医药股份有限公司 2023-01-26 WO disclosed