SCHEMBL31630367

SCHEMBL31630367

Fc1c(CNC2CCC(F)(F)CC2)ccc2ccoc12

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE7B Q9NP56 1/20 0.33
USP2 O75604 1/20 0.31
IDH1 O75874 2/20 0.31
PABPC1 P11940 1/20 0.31
KCNJ1 P48048 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31630244 0.76 BACE1 (0.35) PDE7BUSP2IDH1PABPC1
SCHEMBL31630205 0.73 HTR1B (0.44)
SCHEMBL29559334 0.72 MAOA (0.33)
SCHEMBL31630138 0.71 KDM1A (0.38) PABPC1KCNJ1
SCHEMBL31630318 0.68 RIPK2 (0.35) IDH1
SCHEMBL30200508 0.66 MAOA (0.33)
SCHEMBL21744422 0.64 OPRM1 (0.60)
SCHEMBL31630259 0.61 ACHE (0.51)
SCHEMBL31630161 0.61 POLB (0.65)
SCHEMBL31629954 0.61 CYP3A4 (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025124698-A1 ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2025-06-19 WO disclosed