Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15498651 | 0.81 | ALDH1A1 (0.64) | PDK1ALDH1A1PKMLMNAMAPK1 | |
| SCHEMBL7043142 | 0.80 | CASP6 (0.64) | PDK1TSHRCASP6LMNAAPEX1 | |
| SCHEMBL1223088 | 0.80 | CYP1A2 (0.44) | CYP1A2PDK1ALDH1A1TSHRCASP6 | |
| SCHEMBL7682006 | 0.80 | MAPK1 (0.49) | CYP1A2PDK1ALDH1A1TSHRMAPK1 | |
| SCHEMBL7043138 | 0.80 | CASP6 (0.64) | PDK1TSHRCASP6LMNAAPEX1 | |
| SCHEMBL7047455 | 0.80 | ALOX15 (0.54) | CYP1A2PDK1ALDH1A1TSHRCASP6 | |
| SCHEMBL3528404 | 0.80 | ATM (0.49) | CYP1A2PDK1ALDH1A1TSHRCASP6 | |
| SCHEMBL7047463 | 0.80 | ALOX15 (0.54) | CYP1A2PDK1ALDH1A1TSHRCASP6 | |
| SCHEMBL1223091 | 0.80 | CYP1A2 (0.44) | CYP1A2PDK1ALDH1A1TSHRCASP6 | |
| SCHEMBL27838069 | 0.80 | TSHR (0.55) | PDK1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011207859-A | METHOD FOR PRODUCING 6-BROMO-2-OXYINDOLE OR 6-IODO-2-OXYINDOLE | MANAC INC | 2011-10-20 | — | — | JP | disclosed |