Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1872550 | 0.95 | TDP1 (0.52) | TDP1TSHRALOX15ALDH1A1USP2 | |
| SCHEMBL28294136 | 0.95 | TDP1 (0.52) | TDP1TSHRALOX15ALDH1A1USP2 | |
| Hydrochloric Acid SCHEMBL31437540 | 0.92 | TDP1 (0.50) | TDP1TSHRALOX15ALDH1A1USP2 | |
| Hydrochloric Acid SCHEMBL29191672 | 0.92 | TDP1 (0.50) | TDP1TSHRALOX15ALDH1A1USP2 | |
| SCHEMBL11787700 | 0.86 | TDP1 (0.41) | TDP1TSHRALOX15USP2MAPT | |
| SCHEMBL27361146 | 0.86 | TDP1 (0.41) | TDP1TSHRALOX15ALDH1A1USP2 | |
| SCHEMBL31717978 | 0.86 | TDP1 (0.41) | TDP1TSHRALOX15USP2MAPT | |
| SCHEMBL571574 | 0.84 | MAPT (0.51) | TDP1TSHRALOX15ALDH1A1USP2 | |
| SCHEMBL11814070 | 0.84 | TDP1 (0.44) | TDP1TSHRALOX15ALDH1A1USP2 | |
| SCHEMBL5909594 | 0.81 | TDP1 (0.37) | TDP1TSHRALOX15ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8330039-B2 | Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-11 | — | — | US | disclosed |
| EP-2380208-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. du Pont de Nemours and Company (US) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010085664-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20100180947-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-22 | — | — | US | disclosed |
| US-20070043049-A1 | Substituted heterocyclic diarylamine analogues | NEUROGEN CORPORATION (US) | 2007-02-22 | — | — | US | disclosed |
| US-7179816-B2 | Chemical derivatives and their application as antitelomerase agents | AVENTIS PHARMA S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-20060264433-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | ABBOTT LABORATORIES | 2006-11-23 | — | — | US | disclosed |
| EP-1651636-A1 | SUBSTITUTED HETEROCYCLIC DIARYLAMINE ANALOGUES | NEUROGEN CORPORATION (US) | 2006-05-03 | — | — | EP | disclosed |
| US-20050070575-A1 | Chemical derivatives and their application as antitelomerase agents | AVENTIS PHARMA S.A. (FR) | 2005-03-31 | — | — | US | disclosed |
| US-6858608-B2 | Chemical derivatives and their application as antitelomerase agents | AVENTIS PHARMA S.A. (FR) | 2005-02-22 | — | — | US | disclosed |
| US-4415689-A | PHOTOSTABILIZERS | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| US-4413999-A | CHROMATOGRAPHY, BIOCHEMICAL IMMOBILIZATION, FIBER REACTIVE DYES | RESEARCH PRODUCTS REHOVOT LTD. (IL) | 1983-11-08 | — | — | US | disclosed |
| EP-0084849-A2 | Water soluble copper complexes of disazo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-08-03 | — | — | EP | disclosed |
| EP-0074598-A2 | Synthetic resin compositions containing 2,2,6,6-tetramethyl piperidinyl triazines | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1983-03-23 | — | — | EP | disclosed |
| US-4281103-A | Dicarboxylic acids containing triazine rings, and polyesters formed from these dicarboxylic acids | CIBA-GEIGY CORPORATION (US) | 1981-07-28 | — | — | US | disclosed |
| EP-0025166-A1 | Process for preparing vat dyestuffs of the anthraquinone series, their use in dyeing and printing preparations and in dyeing and printing | CIBA-GEIGY AG (CH) | 1981-03-18 | — | — | EP | disclosed |
| US-4228281-A | PRODUCE THERMOPLASTIC POLYESTERS HAVING HIGH GLASS TRANSITION TEMPERATURES AND HIGH DIMENSIONAL STABILITY UNDER HEAT | CIBA-GEIGY CORPORATION (US) | 1980-10-14 | — | — | US | disclosed |
| US-4086204-A | LIGHT STABILIZERS | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1978-04-25 | — | — | US | disclosed |
| US-4016013-A | OR CARBONITRIDESDECOMPOSITION OF TRIAZINE OR PYRIMIDINE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |
| US-3976603-A | Fluorinated elastomeric polymers containing the 1,3,5-triazine ring, and process for preparing same | MONTEDISON S.P.A. (IT) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043049-A1 | Substituted heterocyclic diarylamine analogues | GPR35, NPY1R, BDKRB1 | TDP1 2752/4885TSHR 138/4885ALOX15 2636/4885 |
| US-20060264433-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | DPP4, DPP3, DPP7 | TDP1 1096/4885TSHR 3551/4885ALOX15 2481/4885 |
| US-20050070575-A1 | Chemical derivatives and their application as antitelomerase agents | TERT, TERF2, DUT | TDP1 85/4885TSHR 3003/4885ALOX15 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.