SCHEMBL24948908

SCHEMBL24948908

COC(=O)c1cc(OCC(F)(F)C(F)(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 6/20 0.35
TRPA1 O75762 2/20 0.35
TRPV1 Q8NER1 1/20 0.35
RBP4 P02753 1/20 0.34
DHODH Q02127 1/20 0.34
CNR2 P34972 1/20 0.34
RORC P51449 1/20 0.34
P2RX7 Q99572 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24949712 0.89 TRPA1 (0.36) MALT1TRPA1TRPV1
SCHEMBL24949786 0.84 TRPA1 (0.36) MALT1TRPA1TRPV1RBP4DHODH
SCHEMBL17417246 0.84 MALT1 (0.36) MALT1RBP4
SCHEMBL1762653 0.82 ALDH1A1 (0.42) TRPA1TRPV1
SCHEMBL45319 0.81 MALT1 (0.37) MALT1TRPA1TRPV1RBP4DHODH
SCHEMBL17417244 0.80 ALDH1A1 (0.37) MALT1RBP4
SCHEMBL29185087 0.80 MALT1 (0.35) MALT1TRPA1TRPV1RBP4DHODH
SCHEMBL29185078 0.80 MALT1 (0.35) MALT1TRPA1TRPV1RBP4DHODH
SCHEMBL867603 0.80 TRPA1 (0.39) MALT1TRPA1TRPV1DHODHP2RX7
SCHEMBL1762495 0.80 L3MBTL1 (0.40) MALT1TRPA1TRPV1RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387449-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-26 EP disclosed
EP-4380363-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-12 EP disclosed
EP-4376616-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-05 EP disclosed
WO-2023021020-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-23 WO disclosed
WO-2023021020-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-23 WO disclosed
WO-2023012081-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-09 WO disclosed
WO-2023006634-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-02 WO disclosed
WO-2023006634-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-02 WO disclosed