SCHEMBL24949786

SCHEMBL24949786

CC(=O)c1cc(OCC(F)(F)P)nn1-c1ncccc1Cl

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 6/20 0.36
TRPV1 Q8NER1 3/20 0.36
MALT1 Q9UDY8 2/20 0.34
SLC16A3 O15427 1/20 0.34
SLC16A1 P53985 1/20 0.34
ALDH1A1 P00352 1/20 0.34
DHODH Q02127 2/20 0.33
P2RX7 Q99572 1/20 0.33
OPRL1 P41146 1/20 0.32
KCNH2 Q12809 1/20 0.32
RBP4 P02753 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24948908 0.84 MALT1 (0.35) TRPA1TRPV1MALT1DHODHP2RX7
SCHEMBL24949712 0.83 TRPA1 (0.36) TRPA1TRPV1MALT1SLC16A3SLC16A1
SCHEMBL1762495 0.82 L3MBTL1 (0.40) TRPA1TRPV1MALT1SLC16A3SLC16A1
SCHEMBL29757297 0.82 L3MBTL1 (0.40) TRPA1TRPV1MALT1SLC16A3SLC16A1
SCHEMBL867603 0.82 TRPA1 (0.39) TRPA1TRPV1MALT1SLC16A3SLC16A1
SCHEMBL1762653 0.82 ALDH1A1 (0.42) TRPA1TRPV1ALDH1A1
SCHEMBL354326 0.79 KDM4E (0.45) TRPA1TRPV1ALDH1A1OPRL1
SCHEMBL12528906 0.79 MALT1 (0.34) TRPA1TRPV1MALT1DHODHRBP4
SCHEMBL27962697 0.79 ALDH1A1 (0.35) TRPA1TRPV1MALT1SLC16A3SLC16A1
SCHEMBL27962696 0.79 ALDH1A1 (0.40) TRPA1TRPV1MALT1SLC16A3SLC16A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023006634-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-02 WO disclosed