Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 5/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | PRKX | P51817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24948901 | 0.76 | ALDH1A1 (0.36) | ALDH1A1HTTBTKTNK2LRRK2 | |
| SCHEMBL30206423 | 0.72 | MAPT (0.46) | ALDH1A1HTTBTKTNK2LRRK2 | |
| SCHEMBL2582880 | 0.72 | MAPT (0.46) | ALDH1A1HTTBTKTNK2LRRK2 | |
| SCHEMBL4072321 | 0.71 | TSHR (0.45) | ALDH1A1HTTBTKLRRK2MAPT | |
| SCHEMBL30961120 | 0.71 | POLB (0.33) | ALDH1A1HTTPOLB | |
| SCHEMBL26851076 | 0.68 | BTK (0.45) | ALDH1A1HTTBTKTNK2LRRK2 | |
| SCHEMBL29232675 | 0.68 | BTK (0.57) | ALDH1A1HTTBTKTNK2LRRK2 | |
| SCHEMBL24785495 | 0.65 | ALDH1A1 (0.62) | ALDH1A1HTTBTKTNK2LRRK2 | |
| SCHEMBL16996713 | 0.65 | TRPA1 (0.42) | ALDH1A1HTTLRRK2PTK2ROCK1 | |
| SCHEMBL25669076 | 0.65 | HTT (0.37) | ALDH1A1HTTPLK4PTK2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006634-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-02 | — | — | WO | disclosed |