Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.58 |
| ▸ | FAAH | O00519 | 5/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2499154 | 0.92 | PTGS1 (0.68) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL28668492 | 0.91 | PTGS1 (0.56) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL28038312 | 0.91 | PTGS1 (0.66) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL9734294 | 0.88 | PTGS1 (0.46) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL1230250 | 0.88 | ALDH1A1 (0.52) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL16579831 | 0.86 | PTGS1 (0.60) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL4618418 | 0.86 | ALDH1A1 (0.50) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL22372519 | 0.85 | PTGS1 (0.73) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL8197865 | 0.85 | PTGS1 (0.69) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL5161619 | 0.85 | MGLL (0.54) | MGLLFAAHPTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572379-B2 | Monomaleimide-functionalized platinum compounds for cancer therapy | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2023-02-07 | — | — | US | disclosed |
| CN-108368143-B | Monomaleimide functionalized platinum compounds for cancer therapy | 维也纳医科大学 | 2022-02-01 | — | — | CN | disclosed |
| US-8029979-B2 | Method for determining the substrate specificity of an enzyme | JPT PEPTIDE TECHNOLOGIES GMBH (DE) | 2011-10-04 | — | — | US | disclosed |
| US-20060234308-A1 | Method for determining the substrate specificity of an enzymatic activity and a device therefor | JERINI AG (DE) | 2006-10-19 | — | — | US | disclosed |
| US-20040171097-A1 | Method for determining the substrate specificity of an enzymatic activity and a device therefor | JERINI AG (DE) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572379-B2 | Monomaleimide-functionalized platinum compounds for cancer therapy | FOLR2, FOLR1, SLC19A1 | MGLL 3581/4885FAAH 3461/4885PTGS1 2894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.