Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PER2 | O15055 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8234472 | 0.94 | PIK3CD (0.63) | PIK3CDTSHRCYP2C19LMNACHRM2 | |
| SCHEMBL31021598 | 0.92 | PIK3CD (0.61) | PIK3CDTSHRCYP2C19LMNACHRM2 | |
| SCHEMBL8283771 | 0.85 | PIK3CD (0.67) | PIK3CDTSHRCYP2C19LMNACHRM2 | |
| SCHEMBL1303006 | 0.83 | PIK3CD (1.00) | PIK3CDTSHRCYP2C19LMNACHRM2 | |
| Bromide SCHEMBL27700849 | 0.82 | PIK3CD (0.96) | PIK3CDTSHRCYP2C19LMNACHRM2 | |
| SCHEMBL11672326 | 0.81 | PIK3CD (0.67) | PIK3CDTSHRCYP2C19LMNACHRM2 | |
| SCHEMBL2794323 | 0.80 | PIK3CD (0.71) | PIK3CDTSHRCYP2C19LMNACHRM2 | |
| SCHEMBL9679884 | 0.80 | PIK3CD (0.71) | PIK3CDTSHRCYP2C19LMNACHRM2 | |
| SCHEMBL27758594 | 0.80 | PIK3CD (0.60) | PIK3CDTSHRCYP2C19LMNACHRM2 | |
| SCHEMBL21294384 | 0.79 | PIK3CD (0.59) | PIK3CDTSHRCYP2C19LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459351-A | Synthesis method of multifunctional N- (aminopropyl) amine compound | 榆林中科洁净能源创新研究院 | 2024-08-09 | — | — | CN | disclosed |
| US-11840497-B2 | 4-(p-quinonyl)-2-hydroxybutanamide derivatives for treatment of mitochondrial diseases | PTC THERAPEUTICS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-20210179542-A1 | 4-(p-QUINONYL)-2-HYDROXYBUTANAMIDE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES | BIOELECTRON TECHNOLOGY CORPORATION | 2021-06-17 | — | — | US | disclosed |
| CN-112080467-A | Tumor infiltrating lymphocytes for adoptive cell therapy | H.李莫菲特癌症中心研究院 | 2020-12-15 | — | — | CN | disclosed |
| CN-106659913-A | Tumor infiltrating lymphocytes for adoptive cell therapy | H.李莫菲特癌症中心研究院 | 2017-05-10 | — | — | CN | disclosed |
| EP-2945950-B1 | ISOMANNIDE DERIVATIVES AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | SANOFI SA (FR) | 2017-03-01 | — | — | EP | disclosed |
| US-9290502-B2 | Pteridines useful as HCV inhibitors and methods for the preparation thereof | JANSSEN SCIENCES IRELAND UC (IE) | 2016-03-22 | — | — | US | disclosed |
| US-20160002406-A1 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | LIVING PROOF, INC. (US) | 2016-01-07 | — | — | US | disclosed |
| CN-101023066-B | Substituted triazines as prion protein ligands and their use to detect or remove prions | PROMETIC BIOSCIENCES LTD | 2013-10-30 | — | — | CN | disclosed |
| EP-1786788-B1 | SUBSTITUTED TRIAZINES AS PRION PROTEIN LIGANDS AND THEIR USE TO DETECT OR REMOVE PRIONS | PROMETIC BIOSCIENCES LTD (GB) | 2012-05-09 | — | — | EP | disclosed |
| US-8030484-B2 | Binding affinity; | PROMETIC BIOSCIENCES LIMITED (GB) | 2011-10-04 | — | — | US | disclosed |
| US-20080269224-A1 | Substituted Triazines as Prion Protein Ligands and Their Use to Detect or Remove Prions | PROMETIC BIOSCIENCES LIMITED (GB) | 2008-10-30 | — | — | US | disclosed |
| CN-101023066-A | Substituted triazines as prion protein ligands and their use to detect or remove prions | PROMETIC BIOSCIENCES LTD (GB) | 2007-08-22 | — | — | CN | disclosed |
| EP-1786788-A1 | SUBSTITUTED TRIAZINES AS PRION PROTEIN LIGANDS AND THEIR USE TO DETECT OR REMOVE PRIONS | Prometic Biosciences Ltd (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006010915-A1 | SUBSTITUTED TRIAZINES AS PRION PROTEIN LIGANDS AND THEIR USE TO DETECT OR REMOVE PRIONS | PROMETIC BIOSCIENCES LIMITED (GB) | 2006-02-02 | — | — | WO | disclosed |
| CN-1438991-A | Cyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase | PFIZER CIMITED (US) | 2003-08-27 | — | — | CN | disclosed |
| EP-1296938-A1 | CYCLOPENTYL-SUBSTITUTED GLUTARAMIDE DERIVATIVES AS INHIBITORS OF NEUTRAL ENDOPEPTIDASE | Pfizer Limited (GB) | 2003-04-02 | — | — | EP | disclosed |
| US-20020052370-A1 | Cyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase | PFIZER, INC. | 2002-05-02 | — | — | US | disclosed |
| WO-2002002513-A1 | CYCLOPENTYL-SUBSTITUTED GLUTARAMIDE DERIVATIVES AS INHIBITORS OF NEUTRAL ENDOPEPTIDASE | PFIZER LIMITED (GB) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269224-A1 | Substituted Triazines as Prion Protein Ligands and Their Use to Detect or Remove Prions | PRNP, CDR2, CRBN | PIK3CD 4881/4885TSHR 215/4885CYP2C19 3469/4885 |
| US-11840497-B2 | 4-(p-quinonyl)-2-hydroxybutanamide derivatives for treatment of mitochondrial diseases | FH, NLN, ACAA2 | PIK3CD 2313/4885TSHR 2679/4885CYP2C19 4284/4885 |
| US-20210179542-A1 | 4-(p-QUINONYL)-2-HYDROXYBUTANAMIDE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES | FH, NLN, ACAA2 | PIK3CD 2313/4885TSHR 2679/4885CYP2C19 4284/4885 |
| US-20020052370-A1 | Cyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase | ENGASE, ENPEP, CPN1 | PIK3CD 4812/4885TSHR 2123/4885CYP2C19 658/4885 |
| US-20160002406-A1 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | AADAT, BCAT2, EBP | PIK3CD 1856/4885TSHR 4165/4885CYP2C19 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.