Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 9/20 | 0.38 |
| ▸ | TUBB | P07437 | 9/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 9/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 9/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 9/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 9/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 9/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 9/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 9/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 9/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 9/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 9/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 9/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 9/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 9/20 | 0.38 |
| ▸ | CTSA | P10619 | 5/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | RORB | Q92753 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495563 | 0.93 | CTSA (0.43) | MGLLTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2501472 | 0.90 | CTSA (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2503497 | 0.89 | MGLL (0.49) | MGLLCTSARORCRORBSCN9A | |
| SCHEMBL2494453 | 0.88 | CTSA (0.47) | MGLLTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2493283 | 0.85 | CTSA (0.45) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2497177 | 0.81 | CTSA (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2498093 | 0.81 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2496589 | 0.81 | CTSA (0.49) | MGLLTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2493513 | 0.79 | CTSA (0.46) | MGLLCTSASCN9AGRM4 | |
| SCHEMBL2493348 | 0.79 | SCN9A (0.50) | CTSASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030339-B2 | Imidazole derivatives for the treatment of anxiety and related diseases | NEUROSEARCH A/S (DK) | 2011-10-04 | — | — | US | disclosed |
| US-20090233929-A1 | Imidazole Derivatives for the Treatment of Anxiety and Related Diseases | NEUROSEARCH A/S (DK) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233929-A1 | Imidazole Derivatives for the Treatment of Anxiety and Related Diseases | GABBR1, GABRB2, GABRB3 | MGLL 4127/4885TUBB4A 1647/4885TUBB 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.