Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 4/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24956350 | 0.76 | FLT3 (0.43) | KDM5BPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL24959068 | 0.76 | KDM5B (0.46) | KDM5BPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL10141530 | 0.73 | KDM5B (0.43) | KDM5BPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL18781279 | 0.70 | PIK3CD (0.46) | KDM5BPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL24956329 | 0.70 | PIM1 (0.43) | KDM5BCREBBPLRRK2JAK2PIM1 | |
| SCHEMBL24956527 | 0.70 | ACHE (0.33) | KDM5BPIK3CDPIK3CAPI4KAPIK3CG | |
| SCHEMBL24958928 | 0.68 | PIK3CD (0.49) | KDM5BPIK3CDPIK3CAPIK3CBPI4KA | |
| Ammonia Solution, Strong SCHEMBL28956673 | 0.67 | PIK3CD (0.51) | KDM5BPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL13171578 | 0.66 | KDM5B (0.39) | KDM5BPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL21610561 | 0.66 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230021705-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230021705-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | KDM5B 2572/4885PIK3CD 778/4885PIK3CA 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.