Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82779 | 0.81 | MAPT (0.50) | GPR119ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL25003025 | 0.80 | MEN1 (0.50) | GPR119ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL27213590 | 0.79 | GPR119 (0.48) | GPR119ALDH1A1L3MBTL1 | |
| SCHEMBL63640 | 0.79 | ALDH1A1 (0.48) | GPR119ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL65161 | 0.79 | LMNA (0.48) | GPR119ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL21538680 | 0.78 | ALDH1A1 (0.47) | GPR119ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL4588281 | 0.78 | GPR119 (0.48) | GPR119EGLN2CKS1BSKP1SKP2 | |
| SCHEMBL63589 | 0.77 | NR1H2 (0.48) | GPR119ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL6486928 | 0.76 | GPR119 (0.46) | GPR119 | |
| SCHEMBL2471189 | 0.75 | MAPT (0.62) | GPR119ALDH1A1MAPTLMNAEGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001247-A1 | PYRIDAZINONE COMPOUND | 南京明德新药研发有限公司 | 2023-01-26 | — | — | WO | disclosed |