Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 5/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | TLK2 | Q86UE8 | 4/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 3/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30155051 | 0.82 | ALDH1A1 (0.49) | MEN1KMT2APDPK1ALDH1A1 | |
| SCHEMBL24966378 | 0.82 | ALDH1A1 (0.49) | MEN1KMT2APDPK1ALDH1A1 | |
| SCHEMBL24967155 | 0.80 | TLK2 (0.57) | MEN1KMT2APDPK1RETPDK1 | |
| SCHEMBL24966362 | 0.80 | TLK2 (0.58) | TLK2 | |
| SCHEMBL24967119 | 0.78 | NPC1 (0.56) | MEN1KMT2APDPK1RETTLK2 | |
| SCHEMBL24967157 | 0.77 | MAP4K1 (0.47) | MEN1KMT2AGSK3BPDPK1TLK2 | |
| SCHEMBL24966370 | 0.67 | PDPK1 (0.64) | GSK3BPDPK1RETPDK1TLK2 | |
| SCHEMBL24966374 | 0.67 | NTRK1 (0.63) | MEN1KMT2APDPK1PDK1TLK2 | |
| SCHEMBL17179651 | 0.65 | MEN1 (1.00) | MEN1KMT2AGSK3BPDPK1RET | |
| SCHEMBL24967153 | 0.64 | PDPK1 (0.56) | GSK3BPDPK1RETMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001942-A1 | 14-3-3 PROTEIN MODULATORS AS ANTITUMOR AGENTS | RAPPOSELLI SIMONA (IT) | 2023-01-26 | — | — | WO | disclosed |