Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042216 | 0.83 | CES2 (0.37) | ALDH1A1LMNAMAPTSMN1; SMN2CYP19A1 | |
| SCHEMBL31386740 | 0.77 | NOTUM (0.39) | JAK2THRBALDH1A1LMNAMAPT | |
| SCHEMBL29020293 | 0.74 | HCAR2 (0.38) | JAK2THRBALDH1A1LMNATSHR | |
| SCHEMBL31633841 | 0.68 | KDM4C (0.39) | MAPTTSHRTTRKDM4E | |
| SCHEMBL5485877 | 0.63 | CA12 (0.42) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL5674660 | 0.62 | KDM4E (0.41) | ALDH1A1LMNAMAPTSMN1; SMN2NOTUM | |
| SCHEMBL9748278 | 0.62 | NOTUM (0.50) | THRBALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL30208649 | 0.62 | KDM4E (0.41) | ALDH1A1MAPTNOTUMKDM4ESELL | |
| SCHEMBL3553024 | 0.62 | CSNK2A2 (0.38) | ALDH1A1TSHRTTRNOTUMGPR17 | |
| SCHEMBL28304328 | 0.62 | JAK2 (0.39) | JAK2THRBALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570612-B2 | Substituted nitrogen heterocyclic compound and anesthetic effect thereof | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2026-03-10 | — | — | US | disclosed |
| US-20230026724-A1 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUND AND ANESTHETIC EFFECT THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
| US-20230026724-A1 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUND AND ANESTHETIC EFFECT THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
| CN-110003188-B | Substituted pyrrole formate derivative and application thereof | 成都麻沸散医药科技有限公司 | 2022-08-26 | — | — | CN | disclosed |
| EP-4043440-A1 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUND AND ANESTHETIC EFFECT THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2022-08-17 | — | — | EP | disclosed |
| CN-112174890-B | Ketone-substituted heterocyclic compounds and their anesthetic action | 成都麻沸散医药科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021068943-A1 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUND AND ANESTHETIC EFFECT THEREOF | 成都麻沸散医药科技有限公司 | 2021-04-15 | — | — | WO | disclosed |
| CN-112174890-A | Ketone-substituted heterocyclic compounds and their anesthetic action | 成都麻沸散医药科技有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-110003188-A | Substituted azole formate ester derivative and application thereof | 成都安诺晨创医药科技有限公司 | 2019-07-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026724-A1 | SUBSTITUTED NITROGEN HETEROCYCLIC COMPOUND AND ANESTHETIC EFFECT THEREOF | CYP21A2, CYP11B1, CYP11B2 | JAK2 1859/4885THRB 1956/4885ALDH1A1 413/4885 |
| US-12570612-B2 | Substituted nitrogen heterocyclic compound and anesthetic effect thereof | CNR1, SCN8A, KCNH1 | JAK2 2220/4885THRB 688/4885ALDH1A1 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.