Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12659858 | 0.79 | ESR1 (0.56) | TDP1MEN1KMT2ANFKB1NFKB2 | |
| SCHEMBL24966596 | 0.76 | ALDH1A1 (0.64) | TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL107624 | 0.75 | ALDH1A1 (0.63) | TDP1KMT2ALMNAL3MBTL1 | |
| SCHEMBL12174587 | 0.73 | KEAP1 (0.67) | FFAR1FFAR4TDP1 | |
| SCHEMBL19035541 | 0.72 | APP (0.49) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL19495808 | 0.72 | KMT2A (0.39) | TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL17128295 | 0.70 | IDO1 (0.58) | — | |
| SCHEMBL24966607 | 0.69 | ALDH1A1 (0.60) | FFAR1FFAR4F2RL1TDP1MEN1 | |
| SCHEMBL23157115 | 0.68 | TP53 (0.42) | MEN1KMT2A | |
| SCHEMBL20420548 | 0.68 | RXFP1 (0.42) | TDP1MEN1KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001223-A1 | COMPOUNDS AND COMPOSITIONS FOR TARGETED THERAPY OF RENAL DISEASES | SHANGHAI MICURX PHARMACEUTICAL CO., LTD. (CN) | 2023-01-26 | — | — | WO | disclosed |