Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | ESR1 | P03372 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19343349 | 0.88 | LMNA (0.53) | LMNAESR1ALDH1A1MAPTNPC1 | |
| SCHEMBL829286 | 0.81 | CYP2C9 (0.50) | LMNAESR1ALDH1A1MAPTNPC1 | |
| SCHEMBL28261662 | 0.80 | LMNA (0.66) | LMNAESR1ALDH1A1MAPTNPC1 | |
| SCHEMBL13531229 | 0.79 | LMNA (0.68) | LMNAESR1ALDH1A1MAPTNPC1 | |
| SCHEMBL14560618 | 0.78 | L3MBTL1 (0.63) | LMNAESR1MAPTRAB9ATSHR | |
| SCHEMBL18769571 | 0.78 | L3MBTL1 (0.44) | LMNAESR1ALDH1A1L3MBTL1GAA | |
| SCHEMBL11612044 | 0.78 | LMNA (0.54) | LMNAALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL7219864 | 0.77 | LMNA (0.62) | LMNAESR1ALDH1A1MAPTNPC1 | |
| SCHEMBL1994995 | 0.77 | ALDH1A1 (0.80) | LMNAESR1ALDH1A1MAPTNPC1 | |
| SCHEMBL22289821 | 0.77 | ESR1 (0.74) | LMNAESR1ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362445-B1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-01-25 | — | — | EP | disclosed |